Milrinone is used in cardiogenic shock primarily as what?

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Prepare for the ECCO Caring for Patients with Cardiovascular Disorders Part 1 Test. Utilize flashcards and multiple-choice questions, complemented by hints and explanations for each query. Gear up for success in your exam!

Multiple Choice

Milrinone is used in cardiogenic shock primarily as what?

Explanation:
Milrinone works as an inodilator by inhibiting phosphodiesterase-3, which raises cAMP in both heart and vessel walls. In cardiac muscle, higher cAMP boosts calcium availability, increasing the strength of contraction (positive inotropy). In vascular smooth muscle, higher cAMP causes relaxation, leading to vasodilation and lower afterload. In cardiogenic shock, this combination improves cardiac output by both pumping harder and easing the ventricle’s workload. It is not a pure vasoconstrictor, not an antiplatelet, and not a beta-blocker.

Milrinone works as an inodilator by inhibiting phosphodiesterase-3, which raises cAMP in both heart and vessel walls. In cardiac muscle, higher cAMP boosts calcium availability, increasing the strength of contraction (positive inotropy). In vascular smooth muscle, higher cAMP causes relaxation, leading to vasodilation and lower afterload. In cardiogenic shock, this combination improves cardiac output by both pumping harder and easing the ventricle’s workload. It is not a pure vasoconstrictor, not an antiplatelet, and not a beta-blocker.

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