What MAP target is generally used in septic shock?

• A. ≥75 mmHg
• B. ≥85 mmHg
• C. ≥65 mmHg
• D. ≥55 mmHg

Answer: (C)

In septic shock, the priority is to preserve organ perfusion by keeping the mean arterial pressure (MAP) at a level high enough to push blood through the microcirculation. After initial fluid resuscitation, the standard target is a MAP of at least 65 mmHg. This level is chosen as a practical balance: it supports perfusion to vital organs like the brain and kidneys while avoiding excessive vasoconstriction from higher targets that could worsen tissue blood flow. Some patients with chronic hypertension may require a higher MAP to maintain adequate perfusion, but 65 mmHg works well for most. If the MAP falls below 65, vasopressors are added to raise it to that threshold. A quick reminder: MAP is roughly calculated as (SBP + 2 × DBP) / 3, reflecting the average pressure driving blood through the organs.